Vaginal natural oxygenation device (VNOD) for concomitant administration of hyaluronic acid and topical hyperbaric oxygen to treat vulvo-vaginal atrophy: a pilot study. | Canada Hyperbarics Skip to main content
RCT European review for medical and pharmacological sciences 2018

Vaginal natural oxygenation device (VNOD) for concomitant administration of hyaluronic acid and topical hyperbaric oxygen to treat vulvo-vaginal atrophy: a pilot study.

Condemi L, Di Giuseppe J, Delli Carpini G, Garoia F, Frega A, Ciavattini A — European review for medical and pharmacological sciences, 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This pilot study evaluated the effectiveness of a vaginal natural oxygenation device (VNOD) delivering hyaluronic acid and topical hyperbaric oxygen therapy for vulvo-vaginal atrophy in 25 postmenopausal patients.

What They Found

Among 25 postmenopausal patients with severe vulvo-vaginal atrophy, significant improvements were observed in well-being (0.3 vs. 5.1, p < 0.001), vaginal burning (0.2 vs. 5.1, p < 0.001), and vaginal elasticity (1.1 vs. 3.8, p < 0.001) from baseline to the end of five biweekly treatments. All patients also reported a recovery of their sexuality after the treatment sessions.

What This Means for Canadian Patients

Canadian patients experiencing severe vulvo-vaginal atrophy might potentially benefit from this novel treatment approach, which combines hyaluronic acid and topical hyperbaric oxygen. This could offer a new non-hormonal option to alleviate symptoms like dryness, burning, and improve sexual well-being.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Italy.

Study Limitations

This was a pilot study with a small sample size of 25 patients, limiting the generalizability of its findings.

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Study Details

Study Type RCT
Category Thermal Burns
Source Pubmed
PubMed ID 30556890
Year Published 2018
Journal European review for medical and pharmacological sciences
MeSH Terms Administration, Intravaginal; Adult; Aged; Atrophy; Dyspareunia; Female; Humans; Hyaluronic Acid; Hyperbaric Oxygenation; Middle Aged; Pilot Projects; Postmenopause; Sexual Behavior; Vagina; Vaginal Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.