Validation and clinical use of the Maquet (Getinge) original series Rotaflow extracorporeal membrane oxygenation device in hyperbaric conditions: a technical report | Canada Hyperbarics Skip to main content
Case Report Diving Hyperb Med 2025

Validation and clinical use of the Maquet (Getinge) original series Rotaflow extracorporeal membrane oxygenation device in hyperbaric conditions: a technical report

Tsouras T, Devaney B, Lin Z, Covelli C, Roberts L, Nanjayya V, et al. — Diving Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Engineers and clinicians at an Australian hospital modified a commercial ECMO (heart-lung bypass) machine to work safely inside a hyperbaric chamber, then used it during 13 HBOT sessions on a critically ill patient with a life-threatening invasive fungal infection.

What They Found

After modifying the power supply, the ECMO device operated safely at up to 243 kPa (approximately 2.4 ATA), with only minor flow variability (up to 180 mL or 10%). No bubbles or equipment failures were detected during pressurization or decompression phases. The patient remained stable and achieved oxygen targets throughout treatment.

What This Means for Canadian Patients

This report shows that critically ill ICU patients on life support can receive HBOT, a treatment previously considered incompatible with ECMO machines. For Canadian patients with severe infections or other conditions requiring both ECMO and HBOT, this technical advance opens a new treatment option that was not previously available.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This describes a single patient case at one center, and the ECMO modifications required specialized engineering expertise that may not be available at most Canadian hyperbaric facilities.

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Study Details

Study Type Case Report
Category Infection
Source Pubmed
PubMed ID 41364855
Year Published 2025
Journal Diving Hyperb Med
MeSH Terms Adult; Humans; Equipment Design; Extracorporeal Membrane Oxygenation; Hyperbaric Oxygenation; Invasive Fungal Infections; Oxygenators, Membrane

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.