What Researchers Did
Researchers conducted a prospective, open-label feasibility study to assess recruitment, tolerance, and safety of hyperbaric oxygen therapy for chronic sequelae after brain injury.
What They Found
Sixty-three participants with chronic stroke, anoxia, or trauma-related brain injury were enrolled, with 53 completing the intervention. The study met feasibility criteria for recruitment, though 44% of participants required additional time to complete the 60 hyperbaric oxygen sessions. HBO2-related adverse events were rare and not serious, and many participants reported symptom improvements, including 51% for memory and 51% for attention/concentration.
Canadian Relevance
This study was conducted in a tertiary academic hospital outside of Canada, with no direct Canadian involvement or specific Canadian patient population.
Study Limitations
As an open-label feasibility study, this trial was not designed to definitively assess the efficacy of hyperbaric oxygen therapy for chronic brain injury sequelae.