A scoring system with high predictive performance for poor outcomes in acute carbon monoxide poisoning | Canada Hyperbarics Skip to main content
Study Sci Rep 2025

A scoring system with high predictive performance for poor outcomes in acute carbon monoxide poisoning

Onda H, Nishino T, Kojima M, Miyake N, Shigeta K, Tominaga N, et al. — Sci Rep, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers developed and tested a four-variable scoring tool (the ABCG score) to predict which carbon monoxide poisoning patients treated with HBOT at 2.8 ATA would have poor outcomes, using data from 176 patients seen over 11 years in Japan.

What They Found

The ABCG score, based on age, presence of burns, C-reactive protein level, and Glasgow coma scale, predicted poor outcomes with 85% sensitivity and 83% specificity. The area under the ROC curve was 0.917, indicating strong discriminative ability, and each of the four variables independently predicted worse outcomes.

What This Means for Canadian Patients

Carbon monoxide poisoning is an OHIP-covered indication for HBOT in Ontario. For Canadian emergency departments treating CO poisoning cases, a simple four-variable score could help triage which patients need more aggressive early intervention or transfer to a hyperbaric facility. Patients arriving with low consciousness, burns, or elevated inflammation markers need the fastest possible treatment.

Canadian Relevance

Carbon monoxide poisoning is a covered OHIP indication for HBOT in Ontario. This scoring tool could support triage decisions in Canadian emergency departments.

Study Limitations

The ABCG score was developed and tested on the same patient population, so it requires external validation in other countries and healthcare settings before adoption.

Was this summary helpful?

Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 40281005
Year Published 2025
Journal Sci Rep
MeSH Terms Humans; Carbon Monoxide Poisoning; Male; Female; Adult; Middle Aged; Hyperbaric Oxygenation; Aged; ROC Curve; Young Adult; Prognosis; Adolescent; Treatment Outcome; Acute Disease

Cite This Study

Share
Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.