What Researchers Did
Researchers conducted a systematic review of 35 randomised and nonrandomized studies to identify and describe interventions for improving or preventing cognitive impairments in adults with brain tumours.
What They Found
The review found that a range of pharmacological agents, including memantine and methylphenidate, and nonpharmacological interventions, such as cognitive rehabilitation and aerobic exercise, were associated with positive effects on cognition. These findings were based on an evaluation of 35 studies identified from a search of nearly 10,000 articles.
Canadian Relevance
This systematic review did not include any studies with a specific Canadian connection or focus.
Study Limitations
Most of the included studies had methodological limitations and were judged to be at moderate-to-high risk of bias, limiting the certainty of the findings.