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Systematic Review Undersea Hyperb Med 2021

Acclimatization to diving: a systematic review

Risberg J — Undersea Hyperb Med, 2021

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Norwegian researchers performed a systematic review of 29 studies to assess whether repeated daily diving or hyperbaric exposure reduces the risk of decompression sickness, a phenomenon called acclimatization.

What They Found

Three epidemiological studies found statistically significant acclimatization to DCS in compressed-air workers over multiple days. Animal studies across six species confirmed the effect. Evidence for acclimatization reducing venous gas embolism in humans was inconsistent, with four studies supporting it and eight finding no significant effect.

Canadian Relevance

Decompression sickness is an OHIP-covered emergency indication for HBOT. Canadian commercial and recreational divers benefit from better understanding of DCS risk factors, including how repeated diving may modulate that risk.

Study Limitations

Study heterogeneity in diving protocols, populations, and outcome definitions makes direct comparison difficult, and the optimal acclimatization schedule to reduce DCS risk in practice remains undefined.

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Study Details

Study Type Systematic Review
Category Decompression Sickness
Source Pubmed
PubMed ID 33975403
Year Published 2021
Journal Undersea Hyperb Med
MeSH Terms Animals; Cats; Dogs; Humans; Rabbits; Rats; Acclimatization; Atmospheric Pressure; Decompression Sickness; Diagnostic Self Evaluation; Diving; Embolism, Air; Goats; Hyperbaric Oxygenation; Incidence; Occupational Diseases; Rats, Sprague-Dawley; Reference Values; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology