Case Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2019

Acute direct traumatic optic neuropathy treated with steroids, minocycline and hyperbaric oxygen: a case report.

Alexander JL, Shulman MD, Sethuraman K — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2019

View Original on PubMed PMID 31683371

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the emergency management of a man who experienced acute vision loss due to direct traumatic optic neuropathy after falling from a height.

What They Found

The patient received immediate hyperbaric oxygen (HBO2), high-dose steroids, and minocycline. After three HBO2 treatments, his vision improved from no light perception to 20/100, further improving to 20/40 after the fourth treatment. At two-month follow-up, his corrected visual acuity was 20/60+2.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from an unspecified location outside of Canada.

Study Limitations

As a single case report, these findings cannot be generalized to a larger patient population and do not provide strong evidence for treatment efficacy.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Ocular / Retinal
Source	Pubmed
PubMed ID	31683371
Year Published	2019
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Accidental Falls; Acute Disease; Adult; Blindness; Combined Modality Therapy; Emergency Treatment; Glucocorticoids; Humans; Male; Methylprednisolone Hemisuccinate; Minocycline; Neuroprotective Agents; Optic Nerve Injuries; Prednisone; Recovery of Function

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology