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Review Pract Neurol 2026

Air embolism to the brain: critical management advice for the neurologist

Wijdicks E, Adusumalli J, Ambrose A — Pract Neurol, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This review article outlines the critical steps for neurologists to recognize, immediately treat, and manage patients experiencing air embolism to the brain.

What They Found

The review details that patients with air embolism to the brain often present with an acute decline in consciousness, new focal neurological deficits like hemiparesis, or a single seizure, potentially leading to deep coma. Immediate management involves positioning the patient in Trendelenburg and left lateral decubitus, along with administering high-flow oxygen (10-15 L/min via mask or up to 60 L/min via nasal cannulae). Hyperbaric oxygen therapy is recommended if available within an 8-hour window, with potential for awakening from coma and improved hemiparesis, though recovery can be slow.

What This Means for Canadian Patients

Canadian patients experiencing symptoms of air embolism, such as sudden changes in consciousness or new neurological deficits, require immediate medical attention. Access to hyperbaric oxygen therapy within an 8-hour window, as recommended by this review, could be crucial for improving outcomes for these patients. This highlights the importance of rapid diagnosis and timely transfer to facilities offering HBOT in Canada.

Canadian Relevance

While this study did not involve Canadian authors or patients, it covers air embolism to the brain, which is a form of arterial gas embolism - a Health Canada-recognized indication for hyperbaric oxygen therapy.

Study Limitations

As a review article, this study synthesizes existing knowledge and provides expert advice rather than presenting new research data or clinical trial results.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 41748327
Year Published 2026
Journal Pract Neurol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.