Case Report J Clin Sleep Med 2016

Altered Sleep Spindles in Delayed Encephalopathy after Acute Carbon Monoxide Poisoning

Yoshiike T, Nishida M, Yagishita K, Nariai T, Ishii K, Nishikawa T — J Clin Sleep Med, 2016

View Original on PubMed PMID 26951423

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers evaluated a 46-year-old man with delayed encephalopathy after carbon monoxide poisoning using neuropsychological tests, neuroimaging, and polysomnography during hyperbaric oxygen therapy.

What They Found

The 46-year-old patient's neurological symptoms improved significantly, but profound frontal cognitive deficits persisted. Polysomnography consistently showed prolonged absence and delayed recovery of sleep spindles throughout the clinical course.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

As a case report, the findings are limited to a single patient and may not be generalizable to the broader population with delayed encephalopathy.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Report
Category	Neurological
Source	Pubmed
PubMed ID	26951423
Year Published	2016
Journal	J Clin Sleep Med
MeSH Terms	Brain; Brain Diseases; Carbon Monoxide Poisoning; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Polysomnography; Sleep Wake Disorders; Time

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Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology