Case Report Tokai J Exp Clin Med 2015

An Adverse Implication of Radiation Therapy for Implant-Retained Maxillofacial Prostheses

Akamatsu T, Hanai U, Kobayashi M, Kuroki T, Tsunoda Y, Miyasaka M — Tokai J Exp Clin Med, 2015

View Original on PubMed PMID 26369259

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on the 19-year postoperative course of a patient who received radiation therapy and underwent reconstruction of a maxillary defect with implant-retained facial prostheses.

What They Found

Initially, two of four implants failed within 4 years and 6 months, with the remaining implants showing bone regression after the patient received 60 Gy of radiation therapy. However, after replacement with Epitec System implants placed in non-irradiated bone, good osseointegration was maintained for 11 years and 6 months.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from Japan.

Study Limitations

As a case report, this study's findings are limited by its focus on a single patient and may not be generalizable to a broader population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Report
Category	Radiation Injury
Source	Pubmed
PubMed ID	26369259
Year Published	2015
Journal	Tokai J Exp Clin Med
MeSH Terms	Aged; Female; Humans; Hyperbaric Oxygenation; Maxilla; Maxillary Neoplasms; Maxillofacial Prosthesis; Maxillofacial Prosthesis Implantation; Orbit; Osseointegration; Prosthesis Failure; Radiotherapy; Radiotherapy Dosage; Plastic Surgery Procedures; Surgical Flaps; Time Factors; Treatment Outcome

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology