Antioxidants may Attenuate Plasma Erythropoietin Decline after Hyperbaric Oxygen Diving | Canada Hyperbarics Skip to main content
RCT Int J Sports Med 2015

Antioxidants may Attenuate Plasma Erythropoietin Decline after Hyperbaric Oxygen Diving

Mutzbauer T, Schneider M, Neubauer B, Weiss M, Tetzlaff K — Int J Sports Med, 2015

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial with 16 healthy male divers to investigate if oral vitamin C and E could attenuate the decline in plasma erythropoietin levels after repeated hyperbaric oxygen dives.

What They Found

In the placebo group (n=8), a moderate decrease in plasma erythropoietin (EPO) was observed from the second day until the end of the study. Conversely, the vitamin group (n=8), receiving 1g ascorbic acid and 600 IU D-α-tocopherol, showed no relevant variations in EPO concentrations compared to baseline.

What This Means for Canadian Patients

For Canadian individuals undergoing hyperbaric oxygen exposure, such as professional divers, supplementing with vitamins C and E might help maintain stable erythropoietin levels. This could potentially mitigate some physiological stress associated with repeated oxygen dives.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study was limited by its small sample size of 16 healthy male divers and short duration, which may limit generalizability to other populations or longer exposures.

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Study Details

Study Type RCT
Category Decompression Sickness
Source Pubmed
PubMed ID 26258821
Year Published 2015
Journal Int J Sports Med
MeSH Terms Administration, Oral; Antioxidants; Ascorbic Acid; Diving; Erythropoietin; Humans; Hyperbaric Oxygenation; Male; alpha-Tocopherol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.