Application of hyperbaric oxygen therapy in a case of prolonged cerebral hypoxia following rapid decompression. | Canada Hyperbarics Skip to main content
Pilot Study Aviation, space, and environmental medicine 1976

Application of hyperbaric oxygen therapy in a case of prolonged cerebral hypoxia following rapid decompression.

Sheffield PJ, Davis JC — Aviation, space, and environmental medicine, 1976

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on the first known case of hyperbaric oxygen therapy used to treat prolonged cerebral hypoxia in a pilot after rapid aircraft decompression.

What They Found

A pilot experienced rapid decompression from 8,000 ft to 45,000 ft, losing consciousness within 5 to 8 seconds and receiving delayed supplemental oxygen after 6 to 8 minutes. He remained blind and disoriented for 6.5 hours until hyperbaric oxygen therapy was administered, after which he regained orientation and vision with negative neurological findings.

Canadian Relevance

This study has no direct Canadian connection as it describes an incident involving a USAF aircraft.

Study Limitations

A significant limitation is that this is a single case report, preventing generalization of its findings to a broader patient population.

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Study Details

Study Type Pilot Study
Category Neurological
Source Pubmed
PubMed ID 971162
Year Published 1976
Journal Aviation, space, and environmental medicine
MeSH Terms Aerospace Medicine; Altitude; Blindness; Decompression Sickness; Diagnosis, Differential; Humans; Hyperbaric Oxygenation; Hypoxia, Brain; Male; Orientation; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology