What Researchers Did
This review summarized current research on brain and spinal cord preconditioning as a strategy to protect against ischaemic injury.
What They Found
Researchers found that preconditioning with volatile anesthetics like isoflurane and xenon showed strong neuroprotection in animal experiments. Additionally, erythropoietin, induced by hypoxic or pharmacological preconditioning, has demonstrated safety and benefit for acute stroke in humans, making it a promising neuroprotective agent.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
As a review, this study synthesizes existing research, much of which is based on animal experiments, and does not present new primary data.