Case Study Frontiers in physiology 2025

Case report: Biphasic autonomic response in decompression sickness: HRV and sinoatrial findings.

Schmitz G — Frontiers in physiology, 2025

View Original on PubMed PMID 40365084

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a case study on a 35-year-old recreational diver who developed neurological decompression sickness and persistent bradycardia, assessing heart rate variability during hyperbaric oxygen therapy and continuous monitoring.

What They Found

During hyperbaric oxygen therapy, the patient initially showed pronounced parasympathetic activity, with an RMSSD of 243 m and HF power of 8,656 m. This was followed by a sympathetic tilt, indicated by an LF/HF ratio of 3.1, and desynchronization revealed by Principal Dynamic Mode analysis. This suggests a biphasic autonomic response in decompression sickness.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, the findings are limited to one individual and may not be generalizable to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Neurological
Source	Pubmed
PubMed ID	40365084
Year Published	2025
Journal	Frontiers in physiology

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology