Case Study Psychosomatics 2014

Catatonia after cerebral hypoxia: do the usual treatments apply?

Quinn DK, Abbott CC — Psychosomatics, 2014

View Original on PubMed PMID 25262046

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This study reported a case of malignant catatonia in a patient with delayed posthypoxic leukoencephalopathy (DPHL) and reviewed existing literature on catatonia in DPHL.

What They Found

Researchers found that a 56-year-old woman with DPHL-related catatonia did not respond to standard treatments, including 10 sessions of electroconvulsive therapy (ECT). A literature review revealed rare success with GABAergic agents for catatonia after cerebral hypoxia, but no cases were successfully treated with ECT, and 7 reports described neurologic decompensation during ECT.

Canadian Relevance

This study has no direct Canadian connection as it is a case report and literature review without Canadian authors, institutions, or patient populations.

Study Limitations

As a case study and literature review of rare occurrences, the findings may not be generalizable to all patients with catatonia after cerebral hypoxia.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Neurological
Source	Pubmed
PubMed ID	25262046
Year Published	2014
Journal	Psychosomatics
MeSH Terms	Amantadine; Brain; Catatonia; Central Nervous System Stimulants; Electroconvulsive Therapy; Female; Humans; Hypoxia, Brain; Leukoencephalopathies; Lorazepam; Magnetic Resonance Imaging; Methylphenidate; Middle Aged; Neuroimaging; Treatment Failure

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology