Cellular and Molecular Targets for Non-Invasive, Non-Pharmacological Therapeutic/Rehabilitative Interventions in Acute Ischemic Stroke. | Canada Hyperbarics Skip to main content
Review International journal of molecular sciences 2022

Cellular and Molecular Targets for Non-Invasive, Non-Pharmacological Therapeutic/Rehabilitative Interventions in Acute Ischemic Stroke.

Onose G, Anghelescu A, Blendea D, Ciobanu V, Daia C, Firan FC, et al. — International journal of molecular sciences, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic literature review to examine the mechanisms and clinical implications of non-invasive, non-pharmacological interventions for acute ischaemic stroke.

What They Found

From an initial pool of 313 articles, 54 fully eligible papers were selected for review, focusing on non-invasive, non-pharmacological interventions for acute ischaemic stroke. These interventions included electro-/acupuncture, hyperbaric oxygen therapy, hypothermia, photobiomodulation, therapeutic gases, and transcranial stimulations, suggesting new therapeutic avenues.

Canadian Relevance

This review does not have a direct Canadian connection.

Study Limitations

A limitation noted was the inclusion of additional bibliographic resources through a non-standardised search beyond the systematic review methodology.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 35055089
Year Published 2022
Journal International journal of molecular sciences
MeSH Terms Biomarkers; Brain; Clinical Decision-Making; Combined Modality Therapy; Cytokines; Disease Management; Disease Susceptibility; Gene Expression Regulation; Humans; Inflammation Mediators; Ischemic Stroke; Neovascularization, Pathologic; Oxidative Stress; Signal Transduction

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology