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Clinical Trial BMC Urol 2019

Clinical and morphological effects of hyperbaric oxygen therapy in patients with interstitial cystitis associated with fibromyalgia

Bosco G, Ostardo E, Rizzato A, Garetto G, Paganini M, Melloni G, et al. — BMC Urol, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers ran an observational clinical trial in 12 patients with both interstitial cystitis and fibromyalgia, giving two cycles of 20 HBOT sessions each at 2 ATA for 90 minutes, measuring quality of life, bladder function, and cystoscopy results before and 6 months after.

What They Found

Most outcomes did not improve significantly. However, bladder capacity during hydrodistension improved significantly (409 mL to 489 mL, p < 0.05). Cystoscopy showed regression of Hunner ulcers and petechiae, suggesting tissue-level healing despite limited symptom relief.

What This Means for Canadian Patients

For Canadian patients with treatment-resistant interstitial cystitis, this small study offers modest encouragement that HBOT may improve bladder tissue health and capacity, even if symptom relief is incomplete. It supports further research rather than routine clinical use.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study had only 12 patients, no control group, and retrospective trial registration -- all of which severely limit the strength of conclusions.

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Study Details

Study Type Clinical Trial
Category Neurological
Source Pubmed
PubMed ID 31690286
Year Published 2019
Journal BMC Urol
MeSH Terms Aged; Cystitis, Interstitial; Female; Fibromyalgia; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Quality of Life

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.