Clinical Study Tissue & cell 2024

Combination use of human menstrual blood stem cell- derived exosomes and hyperbaric oxygen therapy, synergistically promote recovery after spinal cord injury in rats.

Hjazi A, Alghamdi A, Aloraini GS, Alshehri MA, Alsuwat MA, Albelasi A, et al. — Tissue & cell, 2024

View Original on PubMed PMID 38663114

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the combined effects of human menstrual blood stem cell-derived exosomes and hyperbaric oxygen therapy on recovery after traumatic spinal cord injury in 90 male Sprague-Dawley rats.

What They Found

They found that treatment groups, especially the combination group, showed significantly greater numerical density of neurons, higher antioxidative biomarkers (CAT, GSH, SOD), and improved neurological function scores compared to the injury group (P<0.05). The combination therapy also reduced numerical densities of apoptotic and glial cells, and levels of oxidative and proinflammatory factors.

Canadian Relevance

This study has no direct Canadian connection or involvement.

Study Limitations

A primary limitation is that these findings are based on an animal model and may not directly translate to human patients.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	38663114
Year Published	2024
Journal	Tissue & cell
MeSH Terms	Animals; Hyperbaric Oxygenation; Exosomes; Spinal Cord Injuries; Rats; Humans; Rats, Sprague-Dawley; Male; Female; Recovery of Function; Menstruation; Oxidative Stress; Stem Cells

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology