Clinical Study Auris, nasus, larynx 2010

Edaravone, a free radical scavenger, in the treatment of idiopathic sudden sensorineural hearing loss with profound hearing loss.

Sano H, Kamijo T, Ino T, Okamoto M — Auris, nasus, larynx, 2010

View Original on PubMed PMID 19570630

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated whether edaravone, a free radical scavenger, could improve treatment outcomes for idiopathic sudden sensorineural hearing loss (ISSHL) patients with profound hearing loss.

What They Found

In a study involving 14 ISSHL patients treated with edaravone and 14 control patients who received hyperbaric oxygenation therapy, there were no significant differences in hearing recovery between the two groups.

The edaravone group had mean hearing levels equal to or over 90dB at the initial visit.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Japan and did not involve Canadian participants or healthcare settings.

Study Limitations

The study was limited by its small sample size and the retrospective selection of control patients from past records.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Sudden Hearing Loss
Source	Pubmed
PubMed ID	19570630
Year Published	2010
Journal	Auris, nasus, larynx
MeSH Terms	Adult; Aged; Antipyrine; Audiometry, Pure-Tone; Edaravone; Female; Free Radical Scavengers; Hearing Loss, Sensorineural; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Severity of Illness Index; Young Adult

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This study relates to Sudden Sensorineural Hearing Loss. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology