Effect of β2-microglobulin in evaluating the severity and prognosis of brain injury: a clinical study | Canada Hyperbarics Skip to main content
Study BMC Neurol 2022

Effect of β2-microglobulin in evaluating the severity and prognosis of brain injury: a clinical study

Huo Q, Dong W, Gao Y, Zhang Y, Liu X, Yang L, et al. — BMC Neurol, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied 54 brain injury patients and 11 healthy individuals to explore how hyperbaric oxygen therapy affected β2-microglobulin levels in their blood and urine.

What They Found

Before hyperbaric oxygen therapy (HBOT), brain injury patients had significantly higher levels of β2-microglobulin in their blood and urine compared to healthy controls. In patients with conscious disturbance, blood β2-microglobulin levels were higher than in those without, both before and after HBOT. Urine β2-microglobulin levels in the conscious disturbance group were negatively correlated with Glasgow Coma Scale scores (R=-0.351).

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study involved a relatively small number of participants, which may limit the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 36050644
Year Published 2022
Journal BMC Neurol
MeSH Terms Brain Injuries; Glasgow Coma Scale; Humans; Prognosis; Prospective Studies; ROC Curve; beta 2-Microglobulin

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Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology