Clinical Study Acta neurologica Scandinavica 1989

Effect of hyperbaric oxygen treatment on immunological parameters in multiple sclerosis.

Nyland H, Naess A, Eidsvik S, Glette J, Matre R, Hordnes C — Acta neurologica Scandinavica, 1989

View Original on PubMed PMID 2499161

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygen treatment on immunological parameters in 10 multiple sclerosis patients.

What They Found

After 20 hyperbaric oxygen exposures, 10 MS patients showed a significant increase in total and helper T lymphocyte counts in peripheral blood. Granulocytes also exhibited an increased proportion of Fc gamma and C3b receptor-positive cells, with increased oxygen consumption. Serum IgA levels slightly increased, while cerebrospinal fluid parameters remained unchanged.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Norway and published in a European journal.

Study Limitations

A significant limitation of this study is the very small sample size of only 10 patients, which restricts the generalizability of the findings.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	2499161
Year Published	1989
Journal	Acta neurologica Scandinavica
MeSH Terms	Adult; Female; Humans; Hyperbaric Oxygenation; Immunoglobulin Heavy Chains; Immunoglobulin gamma-Chains; Lymphocytes; Male; Multiple Sclerosis

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology