What Researchers Did
Researchers conducted a randomised controlled clinical trial with 52 severe acute stroke patients to evaluate the effects of normobaric hyperoxia administered for the first 12 hours of admission.
What They Found
The study found no significant differences in sex (P=0.5) or stroke type (P=0.2) between the groups. There was no significant difference in Barthel index scores at discharge or six months (P=0.7); however, a significant difference was observed in modified Rankin Scale scores between groups after treatment.
Canadian Relevance
This study has no direct Canadian connection as it was conducted outside of Canada.
Study Limitations
A key limitation of this study is its relatively small sample size of 52 patients, which may limit the generalizability of the findings.