RCT Neurological research 2007

Endothelial-neutrophil interactions during ischemia and reperfusion injury: basic mechanisms of hyperbaric oxygen.

Buras JA, Reenstra WR — Neurological research, 2007

View Original on PubMed PMID 17439696

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed the basic mechanisms by which hyperbaric oxygen inhibits neutrophil-endothelial interactions following ischaemia/reperfusion injury.

What They Found

The review found that hyperbaric oxygen reduces ischaemia/reperfusion injury in various experimental models and in one human randomised clinical trial. A key mechanism identified is the suppression of neutrophil-endothelial adhesion.

Canadian Relevance

This review article has no direct Canadian connection.

Study Limitations

As a review article, this study synthesizes existing literature rather than presenting new experimental data or clinical trial results.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	17439696
Year Published	2007
Journal	Neurological research
MeSH Terms	Animals; Cell Adhesion; Chemotaxis, Leukocyte; Endothelial Cells; Humans; Hyperbaric Oxygenation; Hypoxia-Ischemia, Brain; Microcirculation; Neutrophils; Nitric Oxide; Reperfusion Injury

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology