Entomophthorales infection of the maxillofacial... (1982 study) Skip to main content
Clinical Study The Laryngoscope 1982

Entomophthorales infection of the maxillofacial region.

Nathan MD, Keller AP, Lerner CJ, Davis JC, The Laryngoscope, 1982

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors describe a rare case of a fungal infection in the face and sinus area of a healthy man, likely caused by a fungus called Canidiobolus coronatus.

What They Found

This is a single case report describing a multidisciplinary treatment approach for a rare fungal infection called entomophthoromycosis. The treatment plan consisted of long-term, low-dose amphotericin-B, hyperbaric oxygen, and repeated surgical debridement, chosen because the infection's natural history was poorly documented and the patient had relative intolerance to standard intravenous antifungal therapy. The authors state this is believed to be the first reported case of this infection in the United States. The abstract does not report the patient's outcome or response to treatment.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a single case report with no comparison group and no reported outcome, so no conclusions can be drawn about whether the treatment approach was effective.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 7087645
Year Published 1982
Journal The Laryngoscope
MeSH Terms Amphotericin B; Debridement; Entomophthora; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Mycoses; Nose; Paranasal Sinuses; Tomography, X-Ray Computed

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology