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Clinical Study Pain Med 2021 Canadian

Evaluation of a hyperbaric oxygen therapy intervention in individuals with fibromyalgia

Curtis K, Katz J, Bhatt J, et al. — Pain Med, 2021

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a cohort study at Toronto General Hospital to evaluate the feasibility and safety of hyperbaric oxygen therapy (HBOT) in 18 fibromyalgia patients, comparing immediate HBOT to a delayed treatment arm over 8 weeks.

What They Found

Of 18 randomised patients, 17 completed the study, with mild middle-ear barotrauma reported in three patients and new-onset myopia in four patients. Hyperbaric oxygen therapy demonstrated efficacy in most measured outcomes, including pain, psychological variables, fatigue, and sleep quality, with improvements sustained at the 3-month follow-up.

Canadian Relevance

This study has direct Canadian relevance as it was conducted at the Hyperbaric Medicine Unit at Toronto General Hospital in Ontario, focusing on Canadian patients.

Study Limitations

A primary limitation of this study is its small sample size of 18 patients, which limits the generalizability of the efficacy findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 33594439
Year Published 2021
Journal Pain Med

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology