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Review Respir Care 2013

Evidence for oxygen use in the hospitalized patient: is more really the enemy of good?

Blakeman T — Respir Care, 2013

View Original on PubMed PMID 24064627
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed the existing evidence regarding the efficacy and safety of oxygen administration in hospitalized patients for various medical conditions.

What They Found

The review found evidence supporting oxygen use for hypoxemia, trauma with traumatic brain injury and hemorrhagic shock, cardiac arrest resuscitation, and carbon monoxide poisoning. Recommended S(pO2) targets are 94-98% for most patients, 100% for carbon monoxide poisoning, 88-95% for ARDS, 88-92% for those at risk of hypercapnia, and 88-94% for premature infants.

Canadian Relevance

This study has no direct Canadian connection as it is a general review of evidence for oxygen use in hospitalized patients.

Study Limitations

The review highlights that evidence for oxygen use in many conditions relies on anecdotal experiences, case reports, or small, underpowered studies, necessitating large randomised controlled trials for definitive conclusions.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 24064627
Year Published 2013
Journal Respir Care
MeSH Terms Dose-Response Relationship, Drug; Humans; Hyperbaric Oxygenation; Hypoxia; Oxygen; Oxygen Inhalation Therapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology