Frostbite to the upper limb: An updated review and... (2025 study) Skip to main content
Review Hand Surg Rehabil 2025

Frostbite to the upper limb: An updated review and management recommendations

Saraoui W, Sivakumar B, Forli A, Perruisseau-Carrier A, Hand Surg Rehabil, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed 56 published articles on how doctors diagnose, treat, and prevent frostbite in the upper limb.

What They Found

This literature review found that current frostbite management includes early rapid rewarming, avoiding re-freezing of warmed tissue, wound dressings, and NSAIDs, with thrombolysis using rt-PA and intravenous Iloprost resulting in improved outcomes for patients. Diagnostic tools like arteriography help monitor thrombolysis treatment, technetium-99m scintigraphy supports early prognosis, and newer techniques such as indocyanine green imaging and MRI show promise for improving management. The review states that the potential role of hyperbaric oxygen therapy remains a subject of ongoing research.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a literature review rather than original research, this study summarizes existing publications and does not generate new clinical data or directly test hyperbaric oxygen therapy.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 41109637
Year Published 2025
Journal Hand Surg Rehabil
MeSH Terms Humans; Frostbite; Upper Extremity; Rewarming; Hyperbaric Oxygenation; Thrombolytic Therapy; Anti-Inflammatory Agents, Non-Steroidal

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology