Functional outcome and quality of life after iatrogenic cerebral air embolism treated with hyperbaric oxygen: a prospective cohort study | Canada Hyperbarics Skip to main content
Cohort Study Diving Hyperb Med 2025

Functional outcome and quality of life after iatrogenic cerebral air embolism treated with hyperbaric oxygen: a prospective cohort study

Fakkert R, van Beers L, Weber N, Preckel B, van Hulst R, Weenink R — Diving Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This prospective, single-centre, observational cohort study examined 22 patients with iatrogenic cerebral air embolism (CAE) who were treated with hyperbaric oxygen therapy (HBOT).

What They Found

A total of 22 patients were included, with 14 (64%) having arterial CAE. The overall mortality rate was 23% (n = 5), and only eight of 22 patients achieved full recovery at six months. Nine of 17 survivors (53%) reported a decline in quality of life compared to their pre-incident status.

What This Means for Canadian Patients

Patients experiencing iatrogenic cerebral air embolism face a significant risk of mortality and long-term disability, even with hyperbaric oxygen therapy. This highlights the importance of prompt diagnosis and treatment, as well as the potential for lasting impacts on quality of life.

Canadian Relevance

This study has no direct Canadian connection as it was conducted at a single centre outside of Canada.

Study Limitations

This study's findings are limited by its single-centre, observational design and small sample size of 22 patients.

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Study Details

Study Type Cohort Study
Category Decompression Sickness
Source Pubmed
PubMed ID 41364856
Year Published 2025
Journal Diving Hyperb Med
MeSH Terms Humans; Quality of Life; Hyperbaric Oxygenation; Male; Prospective Studies; Female; Embolism, Air; Middle Aged; Iatrogenic Disease; Glasgow Outcome Scale; Aged; Intracranial Embolism; Treatment Outcome; Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.