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Clinical Study Zentralblatt fur Chirurgie 1999

Gaseous oxygen for protection and conditioning of organs during ischemia.

Isselhard W, Minor T — Zentralblatt fur Chirurgie, 1999

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effectiveness of gaseous oxygen supplied via organ surfaces or vessels for protecting and conditioning various organs during ischaemic storage.

What They Found

Applying high O2 pressures, ileum and lungs maintained function after 48 hours, and hearts after 72 hours of storage, while kidneys and pancreas regained life-supporting functions after 48 and 22 hours, respectively. Using various methods, pancreas was stored for 96 hours, and kidneys damaged by 30 or 60 minutes of warm ischaemia were preserved for 48 and 24 hours, respectively, demonstrating life-supporting functions after transplantation.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or patients.

Study Limitations

The abstract does not explicitly state limitations, but the findings likely represent early experimental or pre-clinical work, requiring further validation in human clinical settings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 10355078
Year Published 1999
Journal Zentralblatt fur Chirurgie
MeSH Terms Aerobiosis; Gases; Heart Transplantation; Humans; Hyperbaric Oxygenation; Hypothermia, Induced; Ileum; Ischemic Preconditioning; Kidney Transplantation; Liver Transplantation; Lung; Myocardium; Organ Preservation; Organ Transplantation; Oxygen

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology