RCT Chin J Traumatol 2001

Glasgow Coma Scale, brain electric activity mapping and Glasgow Outcome Scale after hyperbaric oxygen treatment of severe brain injury

Ren H, Wang W, Ge Z — Chin J Traumatol, 2001

View Original on PubMed PMID 11835741

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers compared 35 patients with severe brain injury who received hyperbaric oxygen therapy to 20 patients who received standard medical care, measuring changes in their brain function and recovery.

What They Found

Patients receiving hyperbaric oxygen therapy showed significant improvements after 3 courses of treatment. Their average Glasgow Coma Scale (GCS) score increased from 5.1 to 14.6, and the abnormal brain electrical activity rate dropped from 94.3% to 38%. The hyperbaric oxygen therapy group also had an 83.7% rate of good to mild disability outcomes, which was significantly better than the control group.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was conducted over two decades ago with a relatively small number of participants, which may limit how broadly its findings can be applied.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	11835741
Year Published	2001
Journal	Chin J Traumatol
MeSH Terms	Adult; Brain Injuries; Brain Mapping; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Prognosis; Treatment Outcome

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Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology