What Researchers Did
Researchers used echocardiography and Doppler to observe hemodynamic changes in ten healthy volunteers during 6 hours of hyperbaric hyperoxia in a compression chamber.
What They Found
After 15 minutes, stroke volume, left atrial diameter, and left ventricular end-diastolic diameter decreased, while left ventricular systolic performance decreased by 10% and meridional wall stress increased by 17%. After 5 hours, compared to sea level, cardiac output decreased and total arterial compliance decreased.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The study was limited by its small sample size of ten healthy volunteers, which may not be representative of a broader population or those with pre-existing conditions.