Hippocampal cerebral blood flow increased following low-pressure hyperbaric oxygenation in firefighters with mild traumatic brain injury and emotional distress | Canada Hyperbarics Skip to main content
Study Neurol Sci 2021

Hippocampal cerebral blood flow increased following low-pressure hyperbaric oxygenation in firefighters with mild traumatic brain injury and emotional distress

Ma J, Hong G, Ha E, Hong H, Kim J, Joo Y, et al. — Neurol Sci, 2021

View Original on PubMed PMID 33532950
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated whether 20 sessions of low-pressure hyperbaric oxygenation (HBO) changed regional cerebral blood flow (rCBF) in the limbic system of firefighters with mild traumatic brain injury (mTBI) and emotional distress.

What They Found

Fourteen firefighters with mTBI and emotional distress who completed HBO treatment showed increased rCBF in the right hippocampal and parahippocampal regions (peak t = 4.31; cluster size = 248 mm3). These regions had lower rCBF at baseline compared to a healthy comparison group (t = -2.20, p = 0.04).

Canadian Relevance

This study did not include Canadian participants or researchers, and therefore has no direct Canadian connection.

Study Limitations

A limitation of this study is the small sample size of only 14 participants who completed the intervention.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 33532950
Year Published 2021
Journal Neurol Sci
MeSH Terms Brain Concussion; Cerebrovascular Circulation; Firefighters; Hippocampus; Humans; Hyperbaric Oxygenation; Psychological Distress

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Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology