Hydrogen peroxide ingestion associated with portal venous gas and treatment with hyperbaric oxygen: a case series and review of the literature. | Canada Hyperbarics Skip to main content
Case Study Clinical toxicology (Philadelphia, Pa.) 2010

Hydrogen peroxide ingestion associated with portal venous gas and treatment with hyperbaric oxygen: a case series and review of the literature.

French LK, Horowitz BZ, McKeown NJ — Clinical toxicology (Philadelphia, Pa.), 2010

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed poison center records from July 1999 to January 2010 to identify and analyze 11 cases of concentrated hydrogen peroxide ingestion treated with hyperbaric oxygen.

What They Found

Among 11 patients who ingested concentrated hydrogen peroxide (10 cases of 35% and 1 case of 12%), all presented with portal venous gas embolism on CT scans. Hyperbaric oxygen treatment successfully resolved portal venous gas bubbles in 9 patients (80%) and nearly resolved them in the remaining two, with 10 patients discharged within one day.

What This Means for Canadian Patients

Patients who accidentally ingest concentrated hydrogen peroxide and develop portal venous gas embolism may benefit from hyperbaric oxygen therapy. This treatment appears effective in resolving gas bubbles and facilitating quick recovery, potentially reducing hospital stays.

Canadian Relevance

This study does not have a direct Canadian connection as it is based on poison center records from the US.

Study Limitations

As a case series, this study is limited by its small sample size and retrospective design, precluding generalizability and definitive conclusions on treatment efficacy.

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Study Details

Study Type Case Study
Category Aging & Longevity
Source Pubmed
PubMed ID 20575671
Year Published 2010
Journal Clinical toxicology (Philadelphia, Pa.)
MeSH Terms Adult; Aged; Aged, 80 and over; Child, Preschool; Embolism, Air; Female; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; Male; Middle Aged; Portal Vein

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.