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Clinical Study Frontiers in neurology 2023

Hyperbaric air mobilizes stem cells in humans; a new perspective on the hormetic dose curve.

MacLaughlin KJ, Barton GP, Braun RK, MacLaughlin JE, Lamers JJ, Marcou MD, et al. — Frontiers in neurology, 2023

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers exposed ten healthy volunteers to hyperbaric air (1.27ATA room air for 90 minutes, 10 times over 2 weeks) to assess its effect on stem progenitor cell mobilization, cytokine expression, and blood counts.

What They Found

Hyperbaric air significantly increased stem progenitor cells (SPCs), showing a 2.5-fold rise after the first exposure and a 7.5-fold increase after nine exposures (p = 0.0001 for both). SPCs remained elevated by 4.5-fold three days post-treatment (p = 0.0001), with increases in IL-6, IL-8, MCP-1, and VEGF, but no changes in complete blood counts.

What This Means for Canadian Patients

This study suggests that hyperbaric air, a non-invasive treatment, can effectively mobilize stem cells, potentially offering a new method to stimulate the body's natural repair processes. For Canadian patients, this could open avenues for future therapies in conditions requiring tissue regeneration or anti-aging interventions, without relying solely on hyperbaric oxygen.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation of this study is its small sample size of ten healthy volunteers, which may not fully represent diverse patient populations or long-term effects.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 37409020
Year Published 2023
Journal Frontiers in neurology

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.