Hyperbaric air mobilizes stem cells in humans; a... (2023 study) Skip to main content
Clinical Study Frontiers in neurology 2023

Hyperbaric air mobilizes stem cells in humans; a new perspective on the hormetic dose curve.

MacLaughlin KJ, Barton GP, Braun RK, MacLaughlin JE, Lamers JJ, Marcou MD, et al., Frontiers in neurology, 2023

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Scientists tested whether breathing pressurized air (not pure oxygen) could increase the number of stem and progenitor cells circulating in the blood of healthy volunteers.

What They Found

This clinical study found that repeated hyperbaric air exposure mobilized stem and progenitor cells (SPCs) and changed cytokine levels in the blood of ten healthy volunteers aged 34 to 35. Participants were exposed to hyperbaric air at 1.27 ATA (4 psig/965 mmHg) for 90 minutes, five days a week, for 10 sessions over two weeks. Blood was drawn at four points: before the first session, right after the first session, just before the ninth session, and three days after the final session, with SPCs identified by blinded scientists using flow cytometry. The researchers concluded that SPCs were mobilized and cytokines were modulated by the hyperbaric air exposure, and stated that hyperbaric air likely is a therapeutic treatment, though the abstract does not report specific fold-changes, p-values, or named cytokines.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study involved only ten healthy volunteers in a narrow age range with no separate control group receiving a different exposure, so the findings may not extend to patients with illness or to other age groups.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 37409020
Year Published 2023
Journal Frontiers in neurology

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology