Hyperbaric oxygen and multiple sclerosis: short-term results of a placebo-controlled, double-blind trial. | Canada Hyperbarics Skip to main content
RCT Lancet (London, England) 1985

Hyperbaric oxygen and multiple sclerosis: short-term results of a placebo-controlled, double-blind trial.

Barnes MP, Bates D, Cartlidge NE, French JM, Shaw DA — Lancet (London, England), 1985

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

In a placebo-controlled, double-blind trial, researchers compared hyperbaric oxygen therapy with normal air for 20 daily sessions in 120 patients with chronic multiple sclerosis.

What They Found

No patients in either the hyperbaric oxygen or control group showed improvement on the Kurtzke disability status scale. However, 12 of 51 (23.5%) patients receiving hyperbaric oxygen and 3 of 47 (6.4%) control patients improved on the subjective bowel/bladder parameter of the Kurtzke functional systems scale.

What This Means for Canadian Patients

This study suggests that hyperbaric oxygen therapy may not significantly improve overall disability in chronic multiple sclerosis. While some patients experienced minor improvements in bladder/bowel symptoms, these effects can often be achieved with standard medications.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

A key limitation is that the study only reported short-term results, not assessing long-term effects of hyperbaric oxygen therapy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 2857361
Year Published 1985
Journal Lancet (London, England)
MeSH Terms Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Multiple Sclerosis; Random Allocation; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.