RCT Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2016

Hyperbaric oxygen for mild traumatic brain injury: Design and baseline summary.

Weaver LK, Chhoeu A, Lindblad AS, Churchill S, Wilson SH — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2016

View Original on PubMed PMID 28768069

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised, double-blind, sham-controlled clinical trial to investigate hyperbaric oxygen therapy for persistent post-concussive symptoms after mild traumatic brain injury in military personnel.

What They Found

The study randomised 71 military personnel between September 2012 and May 2014, with a median age of 33 years and 99% male participants. Baseline data showed 49% of participants had a post-traumatic stress disorder diagnosis, 32% sustained blast injuries, and 73% experienced multiple injuries.

Canadian Relevance

This study was sponsored by the U.S. Department of Defense and does not have a direct Canadian connection.

Study Limitations

A key limitation of this manuscript is that it only describes the study design and baseline characteristics, with primary results still pending.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	28768069
Year Published	2016
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Adult; Brain Concussion; Double-Blind Method; Female; Humans; Hyperbaric Oxygenation; Intention to Treat Analysis; Male; Middle Aged; Military Personnel; Multiple Trauma; Outcome Assessment, Health Care; Post-Concussion Syndrome; Research Design; Safety

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology