Hyperbaric oxygen for moderate-to-severe traumatic brain injury: outcomes 5-8 years after injury | Canada Hyperbarics Skip to main content
Study Med Gas Res 2025

Hyperbaric oxygen for moderate-to-severe traumatic brain injury: outcomes 5-8 years after injury

Zhang Z, Li Z, Li S, Xiong B, Zhou Y, Shi C — Med Gas Res, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively assessed long-term outcomes 5 to 8 years after injury in 133 patients with moderate-to-severe traumatic brain injury who received HBOT during inpatient rehabilitation, analyzing the relationship between number of HBO sessions and functional recovery.

What They Found

62.4% of patients achieved mild or no disability at 5 to 8 year follow-up. Statistical modeling suggested approximately 14 HBOT sessions were optimal for moderate TBI and 21.6 sessions for severe TBI. More sessions beyond the optimal range were associated with worse prognosis.

What This Means for Canadian Patients

TBI is one of the most common causes of long-term disability in Canada. This study suggests HBOT during rehabilitation may reduce disability years later, but raises an important caution: excessive sessions may be counterproductive. Treatment should be individualized rather than pursuing as many sessions as possible.

Canadian Relevance

No direct Canadian connection identified. Relevant to the estimated 400,000 Canadians living with TBI-related disability.

Study Limitations

This retrospective Chinese study may not reflect rehabilitation contexts in Canada; the optimal session numbers were derived from statistical models applied to a non-randomized dataset.

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Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 39324933
Year Published 2025
Journal Med Gas Res
MeSH Terms Adult; Aged; Female; Humans; Male; Middle Aged; Young Adult; Brain Injuries, Traumatic; Hyperbaric Oxygenation; Prognosis; Retrospective Studies; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.