Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study. | Canada Hyperbarics Skip to main content
RCT Stroke 1995

Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study.

Nighoghossian N, Trouillas P, Adeleine P, Salord F — Stroke, 1995

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a double-blind pilot randomised controlled trial with 34 acute ischaemic stroke patients to evaluate the safety and efficacy of hyperbaric oxygen therapy compared to sham treatment over 10 daily sessions.

What They Found

The study randomised 34 patients, with 17 receiving hyperbaric oxygen and 17 receiving sham treatment. Baseline characteristics were similar between groups, and neurological deterioration occurred in 4 patients in the sham group during the first week.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or participants.

Study Limitations

As a pilot study with a small sample size of 34 patients, the generalizability and statistical power of its findings are inherently limited.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 7631339
Year Published 1995
Journal Stroke
MeSH Terms Adult; Aged; Brain Ischemia; Double-Blind Method; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Oxygen; Pilot Projects

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology