Study Restor Neurol Neurosci 2015

Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury

Tal S, Hadanny A, Berkovitz N, Sasson E, Ben-Jacob E, Efrati S — Restor Neurol Neurosci, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed ten patients suffering from chronic neuro-cognitive impairment due to traumatic brain injury (TBI) who underwent 60 daily hyperbaric oxygen therapy (HBOT) sessions, assessing pre- and post-treatment cognitive tests and brain perfusion MRI.

What They Found

Ten post-TBI patients, averaging 10.3±3.2 years post-injury, showed significantly increased cerebral blood flow and cerebral blood volume after HBOT. Clinically, HBOT induced significant improvement in global cognitive scores (p=0.007), with prominent improvements in information processing speed, visual spatial processing, and motor skills.

What This Means for Canadian Patients

This suggests that hyperbaric oxygen therapy could potentially improve brain function and perfusion in Canadian patients suffering from long-term post-concussion syndrome due to TBI. It offers a potential therapeutic avenue for individuals experiencing chronic cognitive impairments years after their injury.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's limitations include its retrospective design and very small sample size of only ten patients.

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Study Details

Study Type	Study
Category	Neurological
Source	Pubmed
PubMed ID	26484702
Year Published	2015
Journal	Restor Neurol Neurosci
MeSH Terms	Adult; Blood Volume; Brain; Cerebrovascular Circulation; Chronic Disease; Cognition Disorders; Female; Humans; Hyperbaric Oxygenation; Magnetic Resonance Angiography; Male; Neovascularization, Physiologic; Neuropsychological Tests; Post-Concussion Syndrome; Regional Blood Flow; Retrospective Studies; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.