Hyperbaric oxygen therapy compared to pharmacological intervention in fibromyalgia patients following traumatic brain injury: a randomized, controlled trial | Canada Hyperbarics Skip to main content
RCT PLoS ONE 2023

Hyperbaric oxygen therapy compared to pharmacological intervention in fibromyalgia patients following traumatic brain injury: a randomized, controlled trial

Ablin JN, Lang E, Engel-Yeger B, et al. — PLoS ONE, 2023

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial comparing hyperbaric oxygen therapy (HBOT) to pharmacological intervention in fibromyalgia patients with a history of traumatic brain injury.

What They Found

Hyperbaric oxygen therapy significantly reduced pain intensity compared to medication (p = 0.001), demonstrating a large net effect size (d = -0.95). HBOT also led to significant improvements in fibromyalgia symptoms, quality of life, and increased pain thresholds and conditioned pain modulation.

What This Means for Canadian Patients

This research suggests that HBOT could offer a new treatment option for Canadian patients with fibromyalgia following TBI, particularly for those who do not respond well to existing medications. It may provide an alternative approach to improve pain, quality of life, and other associated symptoms.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation is that the study focused on fibromyalgia patients with a history of traumatic brain injury, which may limit generalizability to other fibromyalgia populations.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 36897850
Year Published 2023
Journal PLoS ONE

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.