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Case Report Diving Hyperb Med 2025

Hyperbaric oxygen therapy for hypoglycaemic encephalopathy due to insulinoma: a case report

Chu H, Zhang X, Zhao H, Meng X, Wang D, Wang Y — Diving Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Clinicians reported a case of a patient with prolonged consciousness disorder from hypoglycaemic encephalopathy caused by an insulin-secreting pancreatic tumor, who remained unresponsive for 90 days before beginning HBOT.

What They Found

The patient showed recovery of consciousness temporally associated with initiation of HBOT, despite the disorder persisting far longer than the previously reported maximum recovery time of 14 days. All standard treatments including blood sugar correction had been attempted without improvement prior to HBOT.

What This Means for Canadian Patients

This case suggests HBOT may be worth considering for patients with hypoglycaemic brain injury who remain unconscious despite corrected blood sugar levels. For Canadian patients with persistent altered consciousness after severe hypoglycaemia, a hyperbaric consultation may be warranted even in what appears to be a hopeless situation.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a single case report; spontaneous recovery cannot be fully ruled out, and temporal association with HBOT does not prove causation.

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Study Details

Study Type Case Report
Category Neurological
Source Pubmed
PubMed ID 41364869
Year Published 2025
Journal Diving Hyperb Med
MeSH Terms Humans; Brain Diseases; Consciousness Disorders; Hyperbaric Oxygenation; Hypoglycemia; Insulinoma; Pancreatic Neoplasms

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.