Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention. | Canada Hyperbarics Skip to main content
Clinical Study Clinical medicine (London, England) 2021

Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention.

Robbins T, Gonevski M, Clark C, Baitule S, Sharma K, Magar A, et al. — Clinical medicine (London, England), 2021

View Original on PubMed PMID 34862223
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers evaluated the effectiveness of hyperbaric oxygen therapy (HBOT) in 10 patients with long COVID, administering 10 sessions over 12 days and assessing fatigue and cognitive function.

What They Found

Hyperbaric oxygen therapy (HBOT) led to statistically significant improvements in the Chalder fatigue scale (p=0.0059) and global cognition (p=0.0137). Significant improvements were also observed in executive function (p=0.0039), attention (p=0.0020), information processing (p=0.0059), and verbal function (p=0.0098) after 10 sessions.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is its very small sample size of only 10 patients, which limits the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 34862223
Year Published 2021
Journal Clinical medicine (London, England)
MeSH Terms Adolescent; COVID-19; Humans; Hyperbaric Oxygenation; Oxygen; SARS-CoV-2; Post-Acute COVID-19 Syndrome

Cite This Study

Share

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.
J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.
J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.
Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.
PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.
See all Neurological research
View on PubMed Back to Research Library
Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology