Retrospective Study Frontiers in neurology 2025

Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study.

Shabi Shlifer A, Suzin G, Shorer R, Lang E, Finci S, Elman-Shina K, et al. — Frontiers in neurology, 2025

View Original on PubMed PMID 40969214

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed the effects of hyperbaric oxygen therapy (HBOT) on chronic post-concussion symptoms in 26 adults who experienced traumatic brain injury in childhood.

What They Found

The 26 adult participants, with a mean age of 31.7 years, had sustained TBI at an average age of 7.7 years. After receiving at least 40 sessions of HBOT, statistically significant improvements (all adjusted p < 0.001) were observed in global cognition, memory, executive function, attention, and information processing speed.

Canadian Relevance

This study has no direct Canadian connection as it was conducted at a center outside of Canada.

Study Limitations

As a retrospective cohort study, this research is limited by its non-randomised design and potential for selection bias.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Retrospective Study
Category	Neurological
Source	Pubmed
PubMed ID	40969214
Year Published	2025
Journal	Frontiers in neurology

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology