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Retrospective Study Int J Med Sci 2025

Hyperbaric oxygen therapy in children with brain injury: a retrospective case series

Hajek M, Jor O, Tlapak J, et al. — Int J Med Sci, 2025

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers retrospectively assessed the efficacy of hyperbaric oxygen therapy (HBOT) in mitigating symptoms of disability in 21 children with brain injury.

What They Found

Patients showed significant improvement in Glasgow Coma Scale (GCS) from a mean of 10.7 pre-HBOT to 12.3 post-HBOT (p=0.004), and in Glasgow Outcome Scale (GOS) from 3.3 to 3.9 (p<0.001). Among 18 assessed cases, 33% had a large clinically significant response and 39% had a partial response, while 28% showed no response.

What This Means for Canadian Patients

This study suggests hyperbaric oxygen therapy might improve neurological outcomes in children with brain injuries. However, Canadian patients and their families should discuss all treatment options with their healthcare providers, considering the study's preliminary nature.

Canadian Relevance

There is no direct Canadian connection mentioned in this study.

Study Limitations

This retrospective case series involved a small sample size of 21 patients, limiting the generalizability of its findings.

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Study Details

Study Type Retrospective Study
Category Neurological
Source Pubmed
PubMed ID 39898239
Year Published 2025
Journal Int J Med Sci

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.