Pilot Study Cancer 2011

Hyperbaric oxygen treatment improved neurophysiologic performance in brain tumor patients after neurosurgery and radiotherapy: a preliminary report.

Schellart NA, Reits D, van der Kleij AJ, Stalpers LJ — Cancer, 2011

View Original on PubMed PMID 21287528

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a pilot study to assess the effect of hyperbaric oxygen treatment (HBOT) on neurophysiologic performance in ten long-term brain tumour survivors with cognitive deficits after neurosurgery and radiotherapy.

What They Found

After hyperbaric oxygen treatment, the amplitude of the P3b component of late event-related potentials, associated with object interpretation, significantly improved (P = .02). Other neurophysiologic measures, including N200 and P3a amplitudes, latencies, and reaction times, did not show significant changes.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This was a preliminary pilot study with a small sample size of ten patients, limiting the generalizability of the findings.

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Study Details

Study Type	Pilot Study
Category	Neurological
Source	Pubmed
PubMed ID	21287528
Year Published	2011
Journal	Cancer
MeSH Terms	Adult; Aged; Brain Neoplasms; Cognition; Electroencephalography; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Surveys and Questionnaires

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology