Prospective Study Clinical and experimental rheumatology 2019

Hyperbaric oxygen treatment of fibromyalgia: a prospective observational clinical study.

Atzeni F, Casale R, Alciati A, Masala IF, Batticciotto A, Talotta R, et al. — Clinical and experimental rheumatology, 2019

View Original on PubMed PMID 30747099

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers prospectively evaluated the efficacy and safety of 20 hyperbaric oxygen therapy (HBOT) sessions for fibromyalgia patients, assessing symptoms like pain, fatigue, and anxiety.

What They Found

Of the 32 study patients, 28 completed all 20 HBOT sessions. Pain scores and anxiety symptoms significantly improved after both 10 and 20 sessions, while fatigue and fibromyalgia symptom severity significantly improved only after 20 sessions. Sleep quality did not significantly change, and adverse effects were limited.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

This was a prospective observational study with a relatively small sample size and no control group, limiting the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Prospective Study
Category	Neurological
Source	Pubmed
PubMed ID	30747099
Year Published	2019
Journal	Clinical and experimental rheumatology
MeSH Terms	Fibromyalgia; Humans; Hyperbaric Oxygenation; Oxygen; Prospective Studies; Quality of Life; Treatment Outcome

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.

J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.

J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.

Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.

PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.

See all Neurological research

View on PubMed Back to Research Library

Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology