Study Acta Neurol Scand 1986

Hyperbaric oxygenation and erythrocyte antioxidant enzymes in multiple sclerosis patients

Ansari K, Wilson M, Slater G, Haglin J, Kaplan E — Acta Neurol Scand, 1986

View Original on PubMed PMID 3776462

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers measured antioxidant enzyme levels in the red blood cells of multiple sclerosis patients and healthy controls, then observed how hyperbaric oxygen treatments affected these levels in MS patients.

What They Found

They found that multiple sclerosis patients had lower superoxide dismutase activity in their red blood cells compared to neurological controls. After hyperbaric oxygenation at 2 ATA with 100% oxygen, superoxide dismutase activity significantly increased in MS patients. Catalase activity also increased after exposure to both 10% and 100% oxygen at 2 ATA, while glutathione peroxidase activity remained unchanged.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study involved a small number of participants (18 patients) and focused solely on specific enzyme changes rather than clinical improvements.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Study
Category	Neurological
Source	Pubmed
PubMed ID	3776462
Year Published	1986
Journal	Acta Neurol Scand
MeSH Terms	Adult; Aged; Catalase; Erythrocytes; Female; Glutathione Peroxidase; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Multiple Sclerosis; Superoxide Dismutase

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.

J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.

J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.

Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.

PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.

See all Neurological research

View on PubMed Back to Research Library

Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology