Hyperbaric side effects in a traumatic brain injury randomized clinical trial. | Canada Hyperbarics Skip to main content
RCT Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2012

Hyperbaric side effects in a traumatic brain injury randomized clinical trial.

Wolf EG, Prye J, Michaelson R, Brower G, Profenna L, Boneta O — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2012

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers cataloged the side effects of 2.4 atmospheres absolute hyperbaric oxygen versus sham treatment for post-concussion symptoms in military service members with combat-related mild traumatic brain injury.

What They Found

Researchers found that ear block occurred in 5.51% of all exposures (1.09% sham, 5.91% treatment), sinus squeeze in 0.14% (0% sham, 0.27% treatment), and confinement anxiety in 0.27% (0.27% sham, 0.27% treatment). Other mild side effects like headache (0.61%) and nausea (0.2%) were also reported, with no major adverse events such as pulmonary barotrauma or seizures observed.

What This Means for Canadian Patients

Canadian patients considering hyperbaric oxygen therapy for mild traumatic brain injury may be reassured by the low incidence of severe side effects reported in this study. This information can help patients and their healthcare providers weigh the potential benefits against the minimal risks when making treatment decisions.

Canadian Relevance

This study has no direct Canadian connection as it was conducted with military service members in the United States.

Study Limitations

A limitation is that the study population consisted solely of military service members with combat-related traumatic brain injury, which may limit the generalizability of these findings to other patient groups.

Was this summary helpful?

Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 23342764
Year Published 2012
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Adult; Anxiety Disorders; Barotrauma; Brain Injuries; Double-Blind Method; Ear, Middle; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Military Personnel; Paranasal Sinuses; Post-Concussion Syndrome; Single-Blind Method

Cite This Study

Share
Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.