What Researchers Did
Researchers reviewed the detrimental effects of hyperglycemia in acute ischaemic stroke patients and explored various neuroprotective treatments.
What They Found
Hyperglycemia affects approximately one-third of acute ischaemic stroke patients, worsening outcomes by exacerbating neuronal damage, lactic acidosis, reduced blood perfusion, and increased inflammation. While early insulin therapy showed mixed results, recent trials have improved its efficacy, and other treatments like glucagon-like protein-1 administration are emerging.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The abstract indicates that several promising treatments for hyperglycemia in stroke are still in their early stages of development.