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Pilot Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2017

Increased circulating stem cells and better cognitive performance in traumatic brain injury subjects following hyperbaric oxygen therapy.

Shandley S, Wolf EG, Schubert-Kappan CM, Baugh LM, Richards MF, Prye J, et al. — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a pilot clinical study to investigate if hyperbaric oxygen therapy improves cognitive performance and mobilizes stem cells in individuals with persistent cognitive impairment from traumatic brain injury.

What They Found

In 28 subjects with persistent cognitive impairment from mild to moderate traumatic brain injury, hyperbaric oxygen therapy correlated with increased stem cell mobilization. The study also found a correlation between HBO₂ treatment and improved cognitive performance in this population.

What This Means for Canadian Patients

This pilot study suggests that hyperbaric oxygen therapy could potentially offer a new avenue for improving cognitive function in Canadian patients suffering from persistent traumatic brain injury. However, more extensive research is needed to confirm these findings and establish clear treatment protocols before widespread clinical application.

Canadian Relevance

This study has no direct Canadian connection as it was conducted with military personnel deployed to Iraq or Afghanistan.

Study Limitations

As a pilot study with a small sample size of 28 subjects, these findings require further validation through larger, controlled trials.

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Study Details

Study Type Pilot Study
Category Neurological
Source Pubmed
PubMed ID 28779582
Year Published 2017
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms AC133 Antigen; Afghan Campaign 2001-; Antigens, CD34; Brain Injuries, Traumatic; Cell Movement; Cognition; Cognition Disorders; Double-Blind Method; Flow Cytometry; Humans; Hyperbaric Oxygenation; Iraq War, 2003-2011; Military Personnel; Nestin; Neural Stem Cells

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.